Nitric Oxide

Essential for Healthy Circulation

The discovery of Nitric Oxide as the key component in the relaxation of blood vessels led to a Nobel prize in 1998 for Robert Furchgott, Louis Ignarro, and Ferid Murad.

Essentially Nitric Oxide (NO)is the active agent when Nitroglycerine is given for angina and when Viagra is given for erectile dysfunction.  Because it plays such a key role in vascular health, it is important for people to avoid a deficiency.

NO deficiency has been associated with cardiovascular disease (heart attacks), diabetes, stroke, possibly Alzheimer's, and erectile dysfunction.

In the Paleolithic era, NO precursors were provided primarily by root vegetable and green leafy vegetables.  Studies have also shown that Vitamin C increases NO. A study at the The University of Texas Health Science Center at Houston showed that Chinese herbal remedies may work by increasing NO levels.


Japanese people are the longest lived people in the world, with one of the lowest incidences of cardiovascular disease.  An analysis of traditional Japanese food showed that it contains 5 times as many nitrates as a western diet.

In addition, exercise and NO have a synergistic relationship.  Increasing NO increases the ability to exercise (which makes sense since it improves blood flow).  In one study, supplementing NO for 3 days prior to an athletic event increased the athletes performance. Exercise also increases levels of NO.


Unfortunately our modern western diet and lifestyle often lack the nutrients and activities which promote healthy levels of NO.  Understanding where this important molecule comes from and how to increase it is very important.


Incidentally, NO is also a component of air pollution and the discovery of its importance to our health was a surprise.

A simple saliva test can be used to see if a person has a healthy amount of NO.


To review the primary source material for most of this short overview please visit the website below. 

Use this referral code to get free shipping at the Neogenis site: PM00006

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Dr. Franklin Douglis is Board Certified by the American Board of Otolaryngology Head and Neck Surgery (Ear, Nose, and Throat) and has passed his certification in Sleep Medicine.  Dr. Douglis is a recent Diplomate of the American Board of Obesity Medicine.  He attended the University Of Maryland School Of Medicine and completed his specialty training at the University of Maryland Hospital in Baltimore, Maryland. He has a strong interest in general health and overall wellness.  Dr. Douglis has been practicing medicine in Conroe, Montgomery County Texas, Spring, Harris County Texas and the Houston area since 1982.  This site is intended for U.S. Residents only.

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