Medications to Stop Before Allergy Testing

It is important to know what medications to stop before allergy testing because some medications may alter the results of your test.

Stop these oral antihistamines for 5 days before your appointment:

  • Allegra® (Fexofenadine)

  • Atarax®

  • Vistaril® (Hydroxyzine)

  • Zyrtec® (Cetirizine)


Stop these oral antihistamines for 3-4 days before your appointment:

  • Actifed®

  • Dimetapp® (Brompheniramine)

  • Benadryl® (Diphenhydramine)

  • Chlortrimeton® (Chlorpheniramine)

  • Clarinex® (Desloratadine)

  • Claritin® (Loratadine)

  • Phenergan® (Promethazine)

  • Tavist®

  • Antihist® (Clemastine)

  • Actifed®

  • Aller-Chlor®

  • Bromfed®

  • Drixoral®

  • Dura-tab®

  • Novafed-A®

  • Ornade®

  • Poly-Histine-D®

  • Trinalin® (Combination medicines)


If you are taking an oral antihistamine that is not listed stop the medicine for 3-4 days before your allergy test. If you are not sure if the medicine you are taking is an antihistamine ask your doctor.

Stop these medications the night before your allergy skin test:

  • Singulair® (montelukast)

  • Accolate® (zafirlukast)


Stop these medications the morning of your appointment:

  • Zyflo® (zileuton)

  • Tagamet® (cimetadine)

  • Zantac® (ranitidine)

  • Pepcid® (famotidine)

  • Axid® (nizatidine)


Sometimes antidepressants can also act as an antihistamine. Let your doctor know if you are on any antidepressants or any of the medications below before your skin testing.

  • Amitryptyline (Elavil)

  • Clomipramine (Anafranil)

  • Doxepin (Sinequnan)

  • Imipramine (Tofranil)

  • Trimipramine (Surmontil)

  • Amoxapine (Asendin)

  • Desipramine (Nupramin)

  • Nurtiptyline (Pamelor, Aventyl)

  • Protriptyline (Vivactil)

  • Maprotiline (Ludiomil)

  • Mirtazapine (Remeron)

  • Trazadone (Desyrel)

  • Nefazadone (Serzone)


Click the link above to download a printable version of the list of medications to stop prior to allergy testing

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Dr. Franklin Douglis is Board Certified by the American Board of Otolaryngology Head and Neck Surgery (Ear, Nose, and Throat) and has passed his certification in Sleep Medicine.  Dr. Douglis is a recent Diplomate of the American Board of Obesity Medicine.  He attended the University Of Maryland School Of Medicine and completed his specialty training at the University of Maryland Hospital in Baltimore, Maryland. He has a strong interest in general health and overall wellness.  Dr. Douglis has been practicing medicine in Conroe, Montgomery County Texas, Spring, Harris County Texas and the Houston area since 1982.  This site is intended for U.S. Residents only.

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